Smart Drug Delivery Systems: Current Technologies, Clinical Applications, and Future Perspectives in Precision Therapeutics

Abstract

The pharmaceutical industry has come a long way with the introduction of smart drug delivery systems in terms of increasing control level over the therapeutic agents release and measurement of their effects. The recent achievements have demonstrated that these networks are useful in very specific pharmacotherapeutic treatment using high-technological equipment. Various types of diverse classes of delivery systems have been invented including nanoparticulate-based carriers, hydrogel-based matrices and implantable therapeutic systems that are associated with their own advantages in the clinical practice. In current investigations, several technologies has been developed in the controlled theraputic delivery and concomitant work in real time monitoring technology to measure delivery of therapeutic agents. Even though scientific evidence is uniform with regard to the potential of such systems to have a positive effect on therapy, challenges that hinder clinical translation which encompass system stability, biocompatibility determination, and complex regulatory compliance still exist. According to the literature, these limitations can be overcome by implementing artificial intelligence and new technologies in personalized medicine to offer more treatment choices to be administered by intelligent medication systems. It is possible that the evolving character of inventions they can have a significant positive effect on system efficacy and applicability in clinical settings. The available data is indicative of the existence of quantifiable possibilities to improve patient treatment and treatment outcome
in various clinical applications. The paper has an extensive literature review on the existing information on smart drug delivery devices and their mechanisms, types of systems, and use in clinical practice. It evaluates the current findings and describes the colorful prospects of the way of further development of the therapeutic regimes and enhancement of the patient-centered healthcare services.